Healthcare perspectives from The Economist Intelligence Unit
Supporting an innovative life sciences ecosystem in Japan
Medical innovation in the life sciences requires a holistic policy and market access environment that supports everything from basic science to product research and development (R&D) and, ultimately, commercialization. Though North America and Europe have historically led innovation in life sciences, Japan has been a leading contributor from Asia for decades.
Related content
Health system sustainability in Japan: Priorities for structural reform
Japan’s healthcare system has kept the country remarkably healthy with relatively minor changes for nearly six decades. The system provides universal care, generous coverage and the most innovative treatments at a cost that is accessible to all.
Yet the very scope of coverage in the Japanese system obscures the extent to which policymakers have put off making necessary but difficult choices. In particular, the lack of regulation of demand for health services, the pressures of an ageing population and the underdeveloped system for evaluating efficiency and effectiveness of medical products and services could paralyse Japan’s healthcare system as the cost of state-of-the-art medical treatments increase. The economic consequences of this would inevitably reverberate beyond the health system itself.
Without changes in the incentives built into the current system, Japan will struggle to take advantage of medical innovation and to maintain its ability to deliver high-quality, accessible care in the future. As our Health system sustainability in Japan scorecard shows, there are signs that significant fixes to the system may be necessary. Although Japan compares well in many respects to the more expensive and fragmented system in the US, it lags significantly behind the UK and France, and slightly behind neighbouring South Korea, in four of the five principal scoring domains.
Japan’s health system compares especially unfavourably with regard to progress in integrated healthcare and research preparedness, but it also has ground to make up in adequate workforce staffing and in the accountability and patient-centredness of the system. At the same time, it scores well in the provision of a long-term care network. We highlight the report’s key findings below.
Key findings:
Japan’s health financing system is becoming increasingly unsustainable. The country’s existing price review process acts as a brake on structural health system reform. Different incentives are needed to efficiently use medical workforce and hospital resources. Japan’s long-term care system can be a model for other countries but needs better integration with primary care. Japan lags behind developed country peers in the area of research.Download the report to find out more.
Related content
Health system sustainability in Japan: Priorities for structural reform
Japan’s healthcare system has kept the country remarkably healthy with relatively minor changes for nearly six decades. The system provides universal care, generous coverage and the most innovative treatments at a cost that is accessible to all.
Yet the very scope of coverage in the Japanese system obscures the extent to which policymakers have put off making necessary but difficult choices. In particular, the lack of regulation of demand for health services, the pressures of an ageing population and the underdeveloped system for evaluating efficiency and effectiveness of medical products and services could paralyse Japan’s healthcare system as the cost of state-of-the-art medical treatments increase. The economic consequences of this would inevitably reverberate beyond the health system itself.
Without changes in the incentives built into the current system, Japan will struggle to take advantage of medical innovation and to maintain its ability to deliver high-quality, accessible care in the future. As our Health system sustainability in Japan scorecard shows, there are signs that significant fixes to the system may be necessary. Although Japan compares well in many respects to the more expensive and fragmented system in the US, it lags significantly behind the UK and France, and slightly behind neighbouring South Korea, in four of the five principal scoring domains.
Japan’s health system compares especially unfavourably with regard to progress in integrated healthcare and research preparedness, but it also has ground to make up in adequate workforce staffing and in the accountability and patient-centredness of the system. At the same time, it scores well in the provision of a long-term care network. We highlight the report’s key findings below.
Key findings:
Japan’s health financing system is becoming increasingly unsustainable. The country’s existing price review process acts as a brake on structural health system reform. Different incentives are needed to efficiently use medical workforce and hospital resources. Japan’s long-term care system can be a model for other countries but needs better integration with primary care. Japan lags behind developed country peers in the area of research.Download the report to find out more.
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日本のイノベーティブな ライフサイエンス・エコシステムを支えるために
ライフサイエンス・セクターの医療イノベーションには 、 基礎科学・研 究開発(R&D)・実用化など 、 あらゆる領域を対象とした包括的政策や市 場アクセスが不可欠だ。日本は過去数十年にわたり 、 アジアの主要イノ ベーション国として存在感を示してきた。しかしライフサイエンスにお けるイノベーションでは北米と欧州が依然として大きな影響力を保って いる。また近年 、 韓国や中国がインフラ・人材・R&D への投資を加速さ せ 、 新たな政策を打ち出すことでライフサイエンス領域のエコシステム 強化を推進している。競争力強化に向けた抜本的な方策が日本に求めら れているのはそのためだ。
ザ・エコノミスト・インテリジェンス・ユニット(EIU)が作成した本 報告書では 、 日本のライフサイエンス・セクターの現状を米国・韓国・ 中国と比較分析し 、 イノベーション推進体制のさらなる強化に向けた 方策について検証する。
日本はライフサイエンスの分野で高度なイノベーション力を維持して いるが 、 先行する米国には追い付けていない。またアジアでは韓国・ 中国といった競合国の追い上げに直面しており 、 イノベーション大国と しての地位は必ずしも盤石でない。
今回 EIU が行った調査では 、 日本がこれまでの実績を活かしながら ライフサイエンス・セクターのイノベーション・エコシステムを強化し 、 世界的競争力を維持するために求められる方策が明らかとなっている。特に下記の取り組みは重要だ:
高度な研究人材の維持・拡充 研究開発投資の加速と企業向けインセンティブの強化 強固な知的財産保護制度の維持と 、 実施体制・透明性の向上 技術移転・実用化の支援強化 医療財政の健全化と新薬創出の両立
持続可能な医療の実現に向け: 新たな構造改革のビジョン
過去60年、日本は比較的小規模な制度改革により、優れた医療サービスを提供している。国民皆保険制度を通じ、手ごろな価格で最先端の医療サービスを受けられる、つまり高いレベルのユニバーサル・ヘルス・カバレッジ(UHC)を実現してきた。
日本の医療制度の適用範囲が非常に広いために、政策立案者らによる痛みを伴う改革の先延ばしを招いた面もある。先進医療の高額化が進む現在、需給バランス調整メカニズムの欠如、人口の高齢化がもたらす負荷、医療経済性の検討といった大きな課題が浮上している。こうした現状は医療制度、ひいては社会・経済全体の持続可能性に大きな影響を及ぼす可能性が高い。
日本が医療保険制度におけるインセンティブ強化を今進めなければ、先進イノベーションの活用や質の高いUHCの維持が困難になる恐れがある。ザ・エコノミスト・インテリジェンス・ユニット(EIU)が今回作成したスコアカードの結果も、抜本的改革の必要性を示唆している。
日本の医療には、治療費が高額で医療格差の目立つ米国と比較すれば優れた面が多い。しかし制度的な持続可能性を左右する5つの要因のうち4つで英国・フランスに大きな差をつけられており、韓国にも後れを取っているのが現状だ。
Related content
Supporting an innovative life sciences ecosystem in Japan
Medical innovation in the life sciences requires a holistic policy and market access environment that supports everything from basic science to product research and development (R&D) and, ultimately, commercialization. Though North America and Europe have historically led innovation in life sciences, Japan has been a leading contributor from Asia for decades. However, emerging life science sectors in South Korea, and more recently China, are quickly catching up after investing heavily in infrastructure, human capital, and R&D, as well as enacting national policies to further bolster their life sciences ecosystems.
This analysis by The Economist Intelligence Unit explores the enabling factors creating a supportive environment for innovation in the life sciences sector in Japan, benchmarked against three other countries: the US, South Korea, and China.
Overall, while Japan is still producing life science innovation at a high level, it appears to be stagnating while the US remains ahead, and regional competitors are either catching up to or surpassing Japan.
Our research identified several opportunities for Japan to build on early progress in fostering an innovative life sciences ecosystem and remain competitive on the global stage. Priority areas that should be addressed include:
Maintaining and expanding a strong workforce Investing in R&D and incentivising business enterprise Preserving strong intellectual property (IP) protection while enhancing enforcement and transparency Increasing encouragement of technology transfer and commercialisation Ensuring health policies are consistent with those promoting new products
日本のイノベーティブな ライフサイエンス・エコシステムを支えるために
ライフサイエンス・セクターの医療イノベーションには 、 基礎科学・研 究開発(R&D)・実用化など 、 あらゆる領域を対象とした包括的政策や市 場アクセスが不可欠だ。日本は過去数十年にわたり 、 アジアの主要イノ ベーション国として存在感を示してきた。しかしライフサイエンスにお けるイノベーションでは北米と欧州が依然として大きな影響力を保って いる。また近年 、 韓国や中国がインフラ・人材・R&D への投資を加速さ せ 、 新たな政策を打ち出すことでライフサイエンス領域のエコシステム 強化を推進している。競争力強化に向けた抜本的な方策が日本に求めら れているのはそのためだ。
ザ・エコノミスト・インテリジェンス・ユニット(EIU)が作成した本 報告書では 、 日本のライフサイエンス・セクターの現状を米国・韓国・ 中国と比較分析し 、 イノベーション推進体制のさらなる強化に向けた 方策について検証する。
日本はライフサイエンスの分野で高度なイノベーション力を維持して いるが 、 先行する米国には追い付けていない。またアジアでは韓国・ 中国といった競合国の追い上げに直面しており 、 イノベーション大国と しての地位は必ずしも盤石でない。
今回 EIU が行った調査では 、 日本がこれまでの実績を活かしながら ライフサイエンス・セクターのイノベーション・エコシステムを強化し 、 世界的競争力を維持するために求められる方策が明らかとなっている。特に下記の取り組みは重要だ:
高度な研究人材の維持・拡充 研究開発投資の加速と企業向けインセンティブの強化 強固な知的財産保護制度の維持と 、 実施体制・透明性の向上 技術移転・実用化の支援強化 医療財政の健全化と新薬創出の両立
Health system sustainability in Japan: Priorities for structural reform
Japan’s healthcare system has kept the country remarkably healthy with relatively minor changes for nearly six decades. The system provides universal care, generous coverage and the most innovative treatments at a cost that is accessible to all.
Related content
Supporting an innovative life sciences ecosystem in Japan
Medical innovation in the life sciences requires a holistic policy and market access environment that supports everything from basic science to product research and development (R&D) and, ultimately, commercialization. Though North America and Europe have historically led innovation in life sciences, Japan has been a leading contributor from Asia for decades. However, emerging life science sectors in South Korea, and more recently China, are quickly catching up after investing heavily in infrastructure, human capital, and R&D, as well as enacting national policies to further bolster their life sciences ecosystems.
This analysis by The Economist Intelligence Unit explores the enabling factors creating a supportive environment for innovation in the life sciences sector in Japan, benchmarked against three other countries: the US, South Korea, and China.
Overall, while Japan is still producing life science innovation at a high level, it appears to be stagnating while the US remains ahead, and regional competitors are either catching up to or surpassing Japan.
Our research identified several opportunities for Japan to build on early progress in fostering an innovative life sciences ecosystem and remain competitive on the global stage. Priority areas that should be addressed include:
Maintaining and expanding a strong workforce Investing in R&D and incentivising business enterprise Preserving strong intellectual property (IP) protection while enhancing enforcement and transparency Increasing encouragement of technology transfer and commercialisation Ensuring health policies are consistent with those promoting new products
日本のイノベーティブな ライフサイエンス・エコシステムを支えるために
ライフサイエンス・セクターの医療イノベーションには 、 基礎科学・研 究開発(R&D)・実用化など 、 あらゆる領域を対象とした包括的政策や市 場アクセスが不可欠だ。日本は過去数十年にわたり 、 アジアの主要イノ ベーション国として存在感を示してきた。しかしライフサイエンスにお けるイノベーションでは北米と欧州が依然として大きな影響力を保って いる。また近年 、 韓国や中国がインフラ・人材・R&D への投資を加速さ せ 、 新たな政策を打ち出すことでライフサイエンス領域のエコシステム 強化を推進している。競争力強化に向けた抜本的な方策が日本に求めら れているのはそのためだ。
ザ・エコノミスト・インテリジェンス・ユニット(EIU)が作成した本 報告書では 、 日本のライフサイエンス・セクターの現状を米国・韓国・ 中国と比較分析し 、 イノベーション推進体制のさらなる強化に向けた 方策について検証する。
日本はライフサイエンスの分野で高度なイノベーション力を維持して いるが 、 先行する米国には追い付けていない。またアジアでは韓国・ 中国といった競合国の追い上げに直面しており 、 イノベーション大国と しての地位は必ずしも盤石でない。
今回 EIU が行った調査では 、 日本がこれまでの実績を活かしながら ライフサイエンス・セクターのイノベーション・エコシステムを強化し 、 世界的競争力を維持するために求められる方策が明らかとなっている。特に下記の取り組みは重要だ:
高度な研究人材の維持・拡充 研究開発投資の加速と企業向けインセンティブの強化 強固な知的財産保護制度の維持と 、 実施体制・透明性の向上 技術移転・実用化の支援強化 医療財政の健全化と新薬創出の両立
Related content
Supporting an innovative life sciences ecosystem in Japan
Medical innovation in the life sciences requires a holistic policy and market access environment that supports everything from basic science to product research and development (R&D) and, ultimately, commercialization. Though North America and Europe have historically led innovation in life sciences, Japan has been a leading contributor from Asia for decades. However, emerging life science sectors in South Korea, and more recently China, are quickly catching up after investing heavily in infrastructure, human capital, and R&D, as well as enacting national policies to further bolster their life sciences ecosystems.
This analysis by The Economist Intelligence Unit explores the enabling factors creating a supportive environment for innovation in the life sciences sector in Japan, benchmarked against three other countries: the US, South Korea, and China.
Overall, while Japan is still producing life science innovation at a high level, it appears to be stagnating while the US remains ahead, and regional competitors are either catching up to or surpassing Japan.
Our research identified several opportunities for Japan to build on early progress in fostering an innovative life sciences ecosystem and remain competitive on the global stage. Priority areas that should be addressed include:
Maintaining and expanding a strong workforce Investing in R&D and incentivising business enterprise Preserving strong intellectual property (IP) protection while enhancing enforcement and transparency Increasing encouragement of technology transfer and commercialisation Ensuring health policies are consistent with those promoting new products
Designing a vaccine against covid-19: Cautious optimism and lessons from HIV
More from this series
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Covid-19 population tracker: deaths from covid-19 and the ones we must not...
There has been a morbid fascination with the number of deaths associated with covid-19 and the extent to which countries are mishandling the crisis. But we are also facing a data crisis which distorts proper analysis of either.
Scientists are tinkering with models on the expected number of deaths based on incomplete data as not all countries apply the same covid-19 testing rules and not all deaths are accurately recorded. At the same time countries are still deliberating about who they should test, be it asymptomatic cases, only those with symptoms, those presenting to healthcare systems or healthcare workers.
Officials in the US have cast doubt on the numbers being reported by China, and not all countries have the resources to follow the WHO’s “test, test, test” advice. This is particularly true for economies with under-developed healthcare systems such as India, Africa and Latin America.
So with that cautionary note, we have tried to work with the data at hand—incomplete as it is—to map the number of confirmed cases of covid-19 against deaths per 100,000 population over time. While the absolute numbers of deaths are important to note because each loss of life is painful to loved ones, we should also look at death rates across populations to better understand the virus and to keep abreast of potentially effective containment measures. In developing countries cause of death information is often hard to obtain, mostly because systems for recording these details are inadequate or non-existent.
The bubbles represent absolute deaths in an individual country. You can eliminate regions from the timeline to see, for example, how Europe is faring against North America, or zoom in on the trajectory for an individual country. As of April 20th, death rates appear to be highest in Europe with Belgium reaching around 50 deaths per 100,000 population.
While people are still focused on covid-19 deaths, be prepared for a new type of death associated with covid-19 over time. These are deaths and morbidity that will arise as healthcare systems direct more and more resources to covid-19 and less and less to common diseases such as stroke and cancer. For developing countries, the common diseases affected will be tuberculosis, malaria and AIDS.
These “excess” deaths may also arise as people become more fearful of overloading healthcare systems or worried about catching the virus if they attend healthcare facilities including hospitals. There are also the deaths of older people living in residential care facilities or dying at home that are not being properly accounted for. If you have cancer and your treatment is delayed, that is a life and death situation for your overall prognosis. The same applies if treatment is delayed following the first signs of stroke. Patients living with chronic health conditions will see a significant change in the level of service and care received during this crisis, and the damage caused may take years to repair.
So while scientists study the data around covid-19, expect new data to emerge on how other diseases have been affected by this pandemic.
David Miliband: International political response to covid-19 scores “D-minu...
David Miliband is taking refuge in North-west Connecticut during the covid-19 lockdown, but his thoughts are very much global, and inevitably political.
The former UK foreign secretary heads up the International Rescue Committee (IRC), a humanitarian non-governmental organisation (NGO) that works in war-ravaged countries and helps resettle refugees. Refugees, who make up nearly 30% of the world’s 71m “forcibly” displaced people, are especially vulnerable to disease: they have limited access to healthcare, live in poor sanitary conditions and often suffer from pre-existing illnesses. So what needs to be done?
“It's very, very basic,” Mr Miliband says. Are they counted? Are they covered when it comes to testing or healthcare access? Are they assisted by income support schemes or other mechanisms? Do they have rights?
“If the answer to those questions is ‘No’, we know that the consequence is not just a lot of poverty and security violence,” he explains. It also elicits a survivalist response born of desperation. “[People] go underground and they try to make ends meet in any way that they can. And that obviously carries its own dangers, especially in the context of a public health pandemic.”
IRC is working at Cox’s Bazar in Bangladesh. Host to over 1m displaced Rohingya Muslims from neighbouring Myanmar, it is one of the world’s largest and most crowded refugee camps. Social distancing to contain the spread of covid-19 in such camps is, of course, hard.
“I think it would be beyond unfortunate if this [pandemic] was used to further buttress the trend that we've seen in the past 15 years which is what people call democratic recession. And that is the retreat of countries from democratic models.”
“It's easier for the rich than the poor,” Mr Miliband says. “[But] we shouldn't somehow take refuge in the idea that social distancing can't be done so we just shrug our shoulders.”
Where social distancing is more difficult, Mr Miliband explains, hygiene, effective isolation measures and testing become more important: fever testing, at a minimum, and eventually covid-19 testing.
“I also think some social distancing is achieved through masks,” he explains. “It's important that we don't say that because masks are not the whole answer, that they're not any part of the answer. So, in other words, social distancing is more difficult but not impossible.”
In many of the countries where IRC operates, however, Mr Miliband reports a “shocking” lack of covid-19 testing ability. He cites a recent video chat with the IRC team in Somalia who reported that “there have been 700 tests and 436 cases, so a very low number of tests but a very high hit rate”.
Other resources, such as ventilators and intensive care beds, are also scarce. In South Sudan there are only four ventilators for its 11.7m population while Burkina Faso has only 11 for its 19.1m citizens. But the answer is not “trying to send 10,000 ventilators to South Sudan,” Mr Miliband explains.
“Not least because it'll be too late by the time they get there, but because it's a very skilled job to run a ventilator; it takes a whole set of health infrastructure to monitor and implement. So the truth is the prospects for someone who needs a ventilator in South Sudan are utterly grim.”
Political response
Although he works for an international NGO, Mr Miliband remains a political animal. A request to grade the international political response to covid-19 hits a nerve.
“If you are asking me to grade different actions, I have to be grading inactions.The G7 [group of the world's seven largest economies] couldn't agree on a statement because of a ridiculous argument about insistence on calling it a ‘Wuhan virus’. The G20 [which links governments and central banks from 19 countries and the EU] has had one virtual meeting [as of May 1st]. The UN Security Council has not yet been able to agree the resolution to back up the secretary-general’s call in respect of ceasefires. So, it's D-minus territory for the international political response.”
Mr Miliband, whose ministerial tenure included the 2008 financial crisis, is slightly more positive about the economic response to covid-19. He believes there has been “some lesson-learning, but there obviously hasn't been something formally co-ordinated”. Regarding the scientific community, he comments that “there's been a lot of transparency from the scientists, including Chinese scientists, about presenting their data”.
The World Health Organisation (WHO) has faced criticism for its handling of the crisis, but Mr Miliband is forgiving. “Every big organisation [...] will make mistakes, but the real lesson about the WHO is that it's got too little power and too little funding and too little independence—it needs to be able to rectify all three,” he says.
“The lesson is that we need a stronger, better funded, more independent WHO that can speak truth to power.” He considers its year-by-year dependence on donor funding problematic, commenting that endowment with longer-term funding would allow for greater independence.
Geopolitical rivals
The way in which countries have responded to covid-19 will be fuel for global rivalries, Mr Miliband predicts. “I think there’s undoubtedly going to be very significant geopolitical competition in trying to exploit and benefit from comparison coming out of this crisis.”
China’s reputation could come under particular scrutiny, especially given the harsh criticism its handling of the outbreak has received from the US. “I think different parts of the world will trust [China] differently. And of course one question is, ‘How will the world trust China in absolute terms?’, and the second question is, ‘How will you trust China relative to other countries?’”
Mr Miliband believes there was denialism in China at the outbreak of covid-19 and partly attributes this to its one party system. But there is continued denialism in the US, he adds. “Sadly, both democratic and autocratic countries have suffered from denialism.”
The US has reported a striking 79,000-plus deaths from covid-19 (as of May 11th), the highest death toll worldwide. Mr Miliband fears the “continued chaos and [certain] aspects of the American response are going to be used by autocrats around the world to say the democratic systems can't work and can't cope”.
By contrast, South Korea has reported only 256 covid-19 deaths out of a population of 51.3m. Germany, with its 83.7m population, has suffered 7,569 deaths (as of May 11th). Mr Miliband accredits this success to “the power of open societies” to build social trust and organise an effective national response.
“I think it would be beyond unfortunate if this [pandemic] was used to further buttress the trend that we've seen in the past 15 years which is what people call democratic recession. And that is the retreat of countries from democratic models.”
The UK response
So what about the covid-19 response in the UK, Mr Miliband’s home country and political proving ground? The country has the highest number of deaths in Europe at nearly 32,000 (as of May 11th).
“It's really grieving to see the death toll in the UK,” he says. “I think I'm right in saying that around one-eighth of the global death toll is British, even though [less than 1%] of the global population is British. That’s a shocking mismatch.”
There are very serious questions to be answered, he says, about when the lockdown happened, how testing was organised, what happened with contact tracing and the alarm bell that should have been sounded regarding care homes. “Those are all questions which are going to need a very searching set of enquiries.”
Is he confident that Keir Starmer, the new leader of the UK’s Labour party, will hold the government to account? “I think he'll be very good at that. He is a very accomplished lawyer. Britain has a proper opposition for the first time in five years.”
Does he miss politics? Yes, he says, with no hesitation. “In politics and government, you have more power than if you're an NGO—but you also have more obstacles.”
Solidarity in a crisis
Circling back to refugees, does he think attitudes towards them have improved or worsened over time?
“I think it is very mixed,” he says. “Two-thirds of the American public didn't want Jews to be allowed in from Europe in the late 1930s. So that's more or less some of the proportions on the before. But [...] crises [can] bring social solidarity”.
While there are many stark obstacles ahead, Mr Miliband welcomes the fact that some countries are recognising how critical immigrants are to their healthcare systems and broader social structures.
“I think human nature is both fearful and intrigued by people who are different. And you've got to hope that those of us who think life is more interesting because we're not the same don't lose heart.
The world must devise a globally fair covid-19 vaccine allocation system
Vaccination is our best hope for stopping the coronavirus pandemic in its tracks. But producing safe, effective and globally accessible vaccines within the next 12 to 18 months is not only a scientific challenge: new levels of collaboration and investment across industry and government will be essential.
This pandemic is the biggest public health threat that humankind has faced in a century. It is wreaking havoc on societies and economies and it is an acid test for public-private partnerships. We need to move fast to unleash the funding required to develop vaccines.
Delivering covid-19 vaccines for the world—at record speed—will take a collective effort. We must combine the resources and expertise of academia and the private sector with the ability only governments have to mobilise the political will and amass the large sums of money that will be required.
No therapies to prevent or treat covid-19 are available, but research is advancing at a breakneck pace. The private and public sectors must now collaborate to ensure the best and fairest use of new products—wherever they come from—when they arrive.
In the case of vaccines, this means pursuing multiple approaches across both established and new technologies rather than trying to pick one or two “winners” prematurely since many candidate vaccines will inevitably fall by the wayside.
Given the threat posed by covid-19 we must regard vaccines as a global good: a shared resource that is deployed for the good of all irrespective of a country’s ability to pay. Given the global threat posed by covid-19 and the universal, simultaneous need for a vaccine, the world must devise a globally fair allocation system to ensure that healthcare workers and the most vulnerable segments of the world’s population get priority access.
Today, exceptional science is being done around the world. Researchers have been working around the clock to produce vaccine candidates ever since the genome of the new virus was sequenced in January 2020. The good news is this has yielded a flood of more than 90 promising candidates. Now this effort must be buttressed by large-scale public-sector assistance to optimise clinical trial procedures and scale-up manufacturing capacity—something that involves risky upfront investments before any product is approved.
The Oslo-based Coalition for Epidemic Preparedness Innovations (CEPI) provides a platform to deliver just this kind of private-public co-operation. The coalition was initially set up in 2017 after West Africa’s deadly Ebola epidemic to accelerate work on vaccines against emerging infectious diseases.
CEPI—a partnership of governments, industry and philanthropies—has a clear roadmap to accelerate covid-19 vaccine development at an estimated cost of US$2bn over the next 12-18 months. Financial support from the UK, Germany, Norway, Denmark and Finland has brought in around US$660m. Closing the remaining financing gap is imperative if we are to stay on track.
Vaccine development is complex and expensive. Rates of attrition are high. We need multiple candidates to ensure that we can produce safe and effective vaccines. My organisation estimates that a large part of the US$2bn will be needed by the middle of this year to develop eight vaccine candidates through initial phase 1 testing, prepare for phase 2/3 trials and to invest in manufacturing processes for up to six candidates.
Assuming one or more of these candidates succeeds, there will then be a huge global demand requiring unparalleled efforts to harness manufacturing capacity and distribution networks.
Last month, G20 leaders pledged to support the global effort against covid-19, including contributing to this vital vaccine work. The message could not be clearer: now is the time for governments and industry to join forces to fight back against this deadly disease.
Assessing health system preparedness for multiple chronic conditions
“A simple way to start the conversation with a patient with multiple chronic conditions is to ask: ‘If you can get one thing out of this consultation what would it be?"
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Value-based healthcare in Sweden: Reaching the next level
The need to get better value from healthcare investment has never been more important as ageing populations and increasing numbers of people with multiple chronic conditions force governments to make limited financial resources go further.
These pressures, along with a greater focus on patient-centred care, have raised the profile of VBHC, especially in European healthcare systems. Sweden, with its highly comprehensive and egalitarian healthcare system, has been a leader in implementing VBHC from the beginning, a fact that was underscored in a 2016 global assessment of VBHC published by The Economist Intelligence Unit.
This paper looks at the ways in which Sweden has implemented VBHC, the areas in which it has faced obstacles and the lessons that it can teach other countries and health systems looking to improve the value of their own healthcare investments.
Breast cancer patients and survivors in the Asia-Pacific workforce
With more older women also working, how will the rising trend of breast cancer survivorship manifest in workplace policies, practices and culture? What challenges do breast cancer survivors face when trying to reintegrate into the workforce, or to continue working during treatment? How can governments, companies and society at large play a constructive role?
This series of reports looks at the situation for breast cancer survivors in Australia, New Zealand and South Korea. It finds that while progress has been made, more needs to be done, particularly in South Korea, where public stigma around cancer remains high.The Cost of Silence
Cardiovascular diseases levy a substantial financial toll on individuals, their households and the public finances. These include the costs of hospital treatment, long-term disease management and recurring incidence of heart attacks and stroke. They also include the costs of functional impairment and knock-on costs as families may lose breadwinners or have to withdraw other family members from the workforce to care for a CVD patient. Governments also lose tax revenue due to early retirement and mortality, and can be forced to reallocate public finances from other budgets to maintain an accessible healthcare system in the face of rising costs.
As such, there is a need for more awareness of the ways in which people should actively work to reduce their CVD risk. There is also a need for more primary and secondary preventative support from health agencies, policymakers and nongovernmental groups.
To inform the decisions and strategies of these stakeholders, The Economist Intelligence Unit and EIU Healthcare, its healthcare subsidiary, have conducted a study of the prevalence and costs of the top four modifiable risk factors that contribute to CVDs across the Asian markets of China, Australia, Hong Kong, Japan, Singapore, South Korea, Taiwan and Thailand.
Download the report to learn more.
Data and digital technologies to improve clinical outcomes for high-risk cardiovascular patients in Australia
Cardiovascular diseases (CVD) account for around one quarter of deaths in Australia.1 The Economist Intelligence Unit estimates that the annual direct and indirect costs of CVD in Australia totals US$12.3bn.2 There are numerous modifiable risk factors for CVD, but the most important include hypertension (high blood pressure), high cholesterol, tobacco use, diabetes and obesity.3 While much of the recent focus has been on primary prevention through lifestyle modification, those highrisk patients with existing CVD—such as peripheral artery disease or a previou
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The cost of inaction: Secondary prevention of cardiovascular disease in Asi...
The burden of cardiovascular disease (CVD) across Asia-Pacific varies by country, but is nonetheless substantial. Collectively CVD is the leading or second-leading cause of death across the region and the prevalence continues to rise. Further, shifting demographics in the region—with both an increase in younger people experiencing CVD and ageing populations with multiple comorbidities—are putting health systems under increasing pressure.
Progress in tackling the problems associated with CVD has focussed in the primary prevention space, and age-standardised incidence of CVDs are beginning to fall. However, undermining this progress, there is still an unacceptably high recurrence rate of heart attack and stroke with associated economic and human cost. As more patients now survive an initial heart attack or stroke, the secondary event burden is likely to increase. This demands urgent attention but also represents an eminently realisable opportunity to improve care and outcomes in this group.
This analysis by the Economist Intelligence Unit explores the policy response to managing secondary cardiovascular events in eight Asia-Pacific economies: Australia, mainland China, Hong Kong, Japan, Singapore, South Korea, Taiwan and Thailand.
Key findings of the research include:
While CVD policies do exist, some are more comprehensive than others. The success of translating policy on modifiable risk factors into legislation and action, along with measuring impact, is yet to be defined. Government audits are lacking. Primary care systems, a key component for integrated care, are evolving. Rehabilitation services exist but coverage is limited, and they struggle to recruit and retain patients. Integrated, coordinated patient-centred care is a necessary goal. Patient empowerment is essential for success. Maximising data and measuring progress.
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亚太地区心血管疾病二级预防报告
亚太地区心血管疾病的负担因国家/地区而异,但无论任何国家/地区都负担沉重。总体来说,心血管疾病在该地区是造成死亡的首要或次要原因,其患病率也在不断增长。除此以外,该地区人口结构的变化——患心血管疾病的年轻人增加,同时患有多种合并症的老龄人口也呈增长趋势——令医疗系统越来越不堪重负。
应对心血管疾病相关问题的进展主要集中于一级预防领域,同时心血管疾病年龄标准化患病率也正在降低。然而心脏病和卒中复发的几率长期居高不下,令人难以接受,而与之相关的经济和人力成本亦威胁着已经取得的进步。由于越来越多的患者能在心脏病或卒中首次发病时幸存,复发事件所带来的负担很可能会更加沉重。这一状况需要紧急的关注,但同时也带来了一个非常有可能实现的机遇——改善该患者群体所接受的医疗护理及其效果。
本次由经济学人智库(The Economist Intelligence Unit/The EIU)所做的分析探究了亚太地区在管理心血管疾病复发事件上的政策响应措施,研究主要聚焦于以下八个经济体:澳大利亚、中国大陆、中国香港、中国台湾、日本、新加坡、韩国以及泰国。
本研究主要发现包括:
虽然确实存在心血管疾病政策,但有些政策比其他政策更为全面。 将可改变的风险因素有关的政策落实到立法和行动层面的措施是否成功,以及对其影响的评估方法都有待界定。 缺乏政府审计。 初级医疗系统作为综合医疗的关键组成部分,正在不断升级。 康护服务存在但是覆盖范围有限,同时这些项目很难召集和留住患者。 必需确定以患者为中心的综合、协调医疗护理目标. 患者赋权是成功的制胜法宝. 最大程度推进数据和衡量进度.
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조치 부재의 비용: 아시아 태평양 지역 내 심혈관 질환의 2차 예방
아시아 태평양 지역의 심혈관 질환(CVD)부담은 국가별로 상이하나 모두 상당하다.CVD는 지역 전반에서 사망 원인 1위 또는2위를 차지하고 있으며, 유병률도 계속높아지고 있다. 또한 CVD를 경험하는 젊은환자와 여러 동반 이환을 가진 고령화 인구두 집단 모두의 증가라는 지역 내 인구통계적변화로 인해 각국의 보건의료체계에 부하가걸리고 있다.
CVD 관련 문제 해결에 관한 진척은 1차예방 분야에 초점이 맞춰져 이루어져왔으며, CVD의 연령표준화 발생률은감소하기 시작했다. 그러나 여전히 허용할수 없는 높은 수준의 심장마비 및 뇌졸중재발률과 그에 따른 경제적 및 인적 비용이존재해 이러한 진척을 저해하고 있다. 첫심장마비 또는 뇌졸중 생존자가 더많아짐에 따라 2차 사건 관련 부담이증가할 가능성이 높다. 이는 긴급한 주의를요구하는 상황인 동시에, 해당 환자 집단의관리와 결과를 개선할 수 있는 탁월하고현실적인 기회이기도 하다.
본 이코노미스트 인텔리전스 유닛분석에서는 아시아 태평양 지역8개국(호주, 중국, 홍콩, 일본, 싱가포르,한국, 대만, 태국)의 2차 심혈관 사건관리에 대한 정책적 대응을 살펴본다. 본 연구의 주요 결과는 다음을 포함한다. 관련 정책은 확실히 존재하나, 정책이상당히 포괄적인 국가도 있고 그렇지 않은국가도 있다. 조절 가능한 위험인자에 대한 정책을 법률과실천에 성공적으로 반영했는지 여부와 그로인한 영향은 아직 확인되지 않았다. 정부 감사가 결여되어 있다. 통합 관리의 핵심 요소인 1차 의료 체계가발전하고 있다. 재활 서비스가 존재하나 보장 범위가제한적이며, 업체들은 환자 유치와 유지에어려움을 겪고 있다. 필요한 목표는 환자 중심의 통합적이고조정된 관리 환자 권한부여는 성공의 핵심 데이터 극대화 및 진척도 측정亚太地区心血管疾病二级预防报告
亚太地区心血管疾病的负担因国家/地区而异,但无论任何国家/地区都负担沉重。总体来说,心血管疾病在该地区是造成死亡的首要或次要原因,其患病率也在不断增长。除此以外,该地区人口结构的变化——患心血管疾病的年轻人增加,同时患有多种合并症的老龄人口也呈增长趋势——令医疗系统越来越不堪重负。
应对心血管疾病相关问题的进展主要集中于一级预防领域,同时心血管疾病年龄标准化患病率也正在降低。然而心脏病和卒中复发的几率长期居高不下,令人难以接受,而与之相关的经济和人力成本亦威胁着已经取得的进步。由于越来越多的患者能在心脏病或卒中首次发病时幸存,复发事件所带来的负担很可能会更加沉重。这一状况需要紧急的关注,但同时也带来了一个非常有可能实现的机遇——改善该患者群体所接受的医疗护理及其效果。
本次由经济学人智库(The Economist Intelligence Unit/The EIU)所做的分析探究了亚太地区在管理心血管疾病复发事件上的政策响应措施,研究主要聚焦于以下八个经济体:澳大利亚、中国大陆、中国香港、中国台湾、日本、新加坡、韩国以及泰国。
本研究主要发现包括:
虽然确实存在心血管疾病政策,但有些政策比其他政策更为全面。 将可改变的风险因素有关的政策落实到立法和行动层面的措施是否成功,以及对其影响的评估方法都有待界定。 缺乏政府审计。 初级医疗系统作为综合医疗的关键组成部分,正在不断升级。 康护服务存在但是覆盖范围有限,同时这些项目很难召集和留住患者。 必需确定以患者为中心的综合、协调医疗护理目标. 患者赋权是成功的制胜法宝. 最大程度推进数据和衡量进度.
Data and digital technologies to improve clinical outcomes for high-risk ca...
Cardiovascular diseases (CVD) account for around one quarter of deaths in Australia.1 The Economist Intelligence Unit estimates that the annual direct and indirect costs of CVD in Australia totals US$12.3bn.2 There are numerous modifiable risk factors for CVD, but the most important include hypertension (high blood pressure), high cholesterol, tobacco use, diabetes and obesity.3 While much of the recent focus has been on primary prevention through lifestyle modification, those highrisk patients with existing CVD—such as peripheral artery disease or a previous heart attack or stroke—require particular attention to avoid further morbidity and mortality.
The improved use of data and digital health tools has the potential to enable more coordinated and patient-centred models of care. The Digital Health CRC takes this further in saying “research and innovation in digital health offers Australia significant economic and business development opportunities, as well as great promise for the better health of our community”.4
On 27 May 2020, The Economist Intelligence Unit—supported by the Australian Cardiovascular Alliance (ACvA) and Digital Health CRC and with sponsorship from Amgen—convened a virtual roundtable discussion with 25 representatives from across the Australian cardiovascular healthcare landscape.
Co-hosted by the Economist Intelligence Unit with Dr Gemma Figtree, president of ACvA and professor in medicine at University of Sydney & Royal North Shore Hospital, and Dr Tim Shaw, director of research and workforce capacity at Digital Health CRC, the roundtable aimed to identify barriers, challenges and opportunities to improve outcomes for highrisk CVD patients by improving the use of data and digital technologies.
1 Australian Institute of Health and Welfare. Cardiovascular disease. In: Welfare AIoHa, editor. Canberra 2019. 2 Economist Intelligence Unit. “The cost of silence: Cardiovascular disease in Asia”, 2019 3 Centers for Disease Control and Prevention. “Know your risk for heart diseases”. Available from: https://www.cdc.gov/heartdisease/risk_factors.htm (Accessed Jun 2020). 4 Digital Health CRC. “About us”. Available from: https://www.digitalhealthcrc.com/about-us/ (Accesed Jun 2020).